Complement-targeted therapy: development of C5- and C5a-targeted inhibition
نویسندگان
چکیده
منابع مشابه
Complement-targeted therapy: development of C5- and C5a-targeted inhibition
The complement system is a major effector of humoral immunity and natural immunity. The complement system has three independent pathways of complement activation: a classical pathway, an alternative pathway, and a lectin pathway. These pathways converge to a common pathway that activates C3. This pathway also leads to the formation of various bioactive molecules such as C5a and the formation of...
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ژورنال
عنوان ژورنال: Inflammation and Regeneration
سال: 2016
ISSN: 1880-8190
DOI: 10.1186/s41232-016-0013-6